Some Nitrous Oxide References
Stacey et al (1992) Methionine in the treatment of nitrous oxide induced neuropathy and myeloneuropathy Journal of Neurology 239:401-403.
NIH Citation . Article PDF
http://www.ncbi.nlm.nih.gov/pubmed/1506823 - 20 deaths. http://www.ncbi.nlm.nih.gov/pubmed/2401921 - 11 deaths, workplace misuse of nitrous. http://www.ncbi.nlm.nih.gov/pubmed/7797187 - 1 death, accidental asphyxia. http://www.ncbi.nlm.nih.gov/pubmed/26258592 - 2 deaths, asphyxia from gas masks covering the face. FROM CHOCOLATE TO MORPHINE: Andrew Weil & Winifred Rosen. Make sure you get the 1993 edition. It's the one with the horrible sub-title "Everything You Need To Know About Mind-Altering Drugs". The sub-title's wrong, but it's still a good reference. A PRIMER OF DRUG ACTION: Robert M. Julien. I believe it's in the fifth edition right now, but I don't know. Pulsson (1979) "Recreational" misuse of nitrous oxide, J. Am Dent. Soc. 98:410-411 Sahenk et al.(1978) "Polyneuropathy from inhalation of N2O cartridges through a whipped cream dispenser" Neurology 28:485-487. Annals of Internal Medicine, Vol 96, 3,Mar 1982, pp333-334:Home made Nitrous Oxide: No laughing matter. Gillman, M.A. Nitrous oxide abuse in perspective Clinical Neuropharmacol. 1992, 15:297-306 Dohrn, C.S., Lichtor, J.L., Finn, R.S., Uitvlugt, A., Coalson, D.W., Rupani, G., de Wit, H. and Zacny, J.P. Subjective and psychomotor effects of nitrous oxide in healthy volunteers Behavioural Pharmacology 1992,3:19-30 1. Barker, George T. Instructions in the preparation, administration, and properties of nitrous oxide, protoxide of nitrogen, or laughing gas. 3rd ed. [Philadelphia] Rubencame and Barker, 1870. UCSF Library RD86.N7 B2 1870 Books 2. DISSERTATION Barton, William Paul Crillon, 1786-1856. A dissertation on the chymical properties and exhilerating effects of nitrous oxide gas; and its application to pneumatick medicine ... Philadelphia, Printed for the author, at the Lorenzo Press, 1808. UCD HealthSci micro film 200 reel 6 no.144 Microform UCSF Library micro- film 658 History Media 3. Bourne, James Gerald. Nitrous oxide in dentistry : its danger and alternatives / J. G. Bourne. Chicago : Year Book Publishers, 1960. UCSF Library RK512.N55 B67 1960 Books 4. Davy, Humphry, Sir, 1778-1829. Researches, chemical and philosophical; chiefly concerning nitrous oxide, or dephlogisticated nitrous air, and its respiration, by Humphry Davy ... London, Printed for J. Johnson by Briggs and Cottle, 1800. UCLA Biomed WZ 260 D268r 1800 Rare Library has: Library's copy has duplicate p.541-542 after p.580 5. Eastwood, Douglas W. Nitrous oxide. Philadelphia, F.A. Davis Co. . Series title: Clinical anesthesia 1/1964. UCD HealthSci WO205 C65 1964 no.1 UCSF Library RD81.A1 C64 v.1 1964 Books 6. Nitrous oxide/N2O / edited by Edmond I. Eger II. New York : Elsevier, c1985. UCD HealthSci QV81 N58 1985 UCI Biomed QV 81 N731 1985 UCLA Biomed QV 81 N731 1985 UCSD Biomed QV 81 N731 1985 UCSF Library RD86.N7 N58 1985 Books CSL Main Lib RD86.N7 N58 1985 General Coll 7. Shedlin, Michael. Laughing gas (nitrous oxide); historical and recent essays on the practice of inhaling nitrous oxide. Edited by Michael Shedlin & David Wallechinsky, with Saunie Salyer. [1st ed. n.p.] And/Or Press . UCD HealthSci QV81 S53 UCSB Main Lib RD86.N7 S53 Sci-Eng 8. Smith, W. D. A. Under the influence : a history of nitrous oxide and oxygen anaesthesia / W.D.A. Smith. London : Scientific and Medical Division, Macmillan, 1982. UCD HealthSci WO211.1 S65 1982 UCI Biomed WO 211.1 S663u 1982 UCLA Biomed WO 211.1 S663u 1982 Hist Div UCSD Biomed WO 211.1 S663u 1982 UCSF Library RD79 .S65 1982 History Lancet, Vol.2 no.8102, 9 Dec. 1978, pg 1227-1230, Myeloneuropathy after prolonged exposure to nitrous oxide. --the B12 deficiency. Doesn't look like a real problem without very heavy use or very low B12 levels. Lancet, Aug12, 1978, pg339-342, Megaloblastic hemopoiesis in patients receiving nitrous oxide. --B12 metabolism Anaesthesiology, 1978, Dec67(6) 960-964, --sorry, havn't got the title, this is about teratogenic effects in rats. Anaesthesia, 34, 1979, pg147-151, --nitrous hazardous for patients with ear surgery or ear disease. Forgot to mention this problem in the previous post. Does not appear to be a problem if your ears are healthy. Seminars in Surgical Oncology, 1990, 6(3), 141-147 --cancer, cause or cure? Havn't read this one (not in the local library). Abuse of volatile substances, information paper 2, (Australian) Commonwealth Department of Health, Drugs of Dependency branch, 1984, --this is a great reference, a small booklet on N2O, patterns of abuse, obtainability, toxicity and side effects, etc. Probably difficult to get outside of Australia, but worth trying for. Acta Anae. Scand. 1985 29 pg 635-638, --study on volunteers looking at acute tolerance, subjective and objective observations. Review of inhalants: Euphoria to Dysfuntion, Sharp, C.W. and Brehm, M. L. (editors), NIDA research monograph no.15, U.S. Government Printing Office, October 1977 --this contains two articles, Abuse of Inhalation Anaesthetic drugs, by M.B. Chenoweth, and Preclinical Behavioural toxicology of Inhalant solvents, by R.E. Bowman, that are probably worthwhile. American Journal of Forensic Medical Pathology, 1988, Mar 9(1), pg 60-63, Death by nitrous oxide: an interesting case of auto-eroticism --sounds amusing. 1989, Dec 10(4), pg 330-331, --another suicide case